Addiction is a primary, chronic disease of brain reward, motivation, memory and related circuitry. Dysfunction in these circuits leads to characteristic biological, psychological, social and spiritual manifestations. This is reflected in an individual pathologically pursuing reward and/or relief by substance use and other behaviours.
Addiction is characterized by the inability to consistently abstain, impairment in behavioural control, craving, diminished recognition of significant problems with one’s behaviours and interpersonal relationships, and a dysfunctional emotional response. Like other chronic diseases, addiction often involves cycles of relapse and remission. Without treatment or engagement in recovery activities, addiction is progressive and can result in disability or premature death.
The definition of drug addiction refers to the obsessive and repeated use of dangerous amounts of drugs and the appearance of withdrawal symptoms when not using drugs. The effects of drug addiction seen, due to this compulsion, are wide-ranging and profound. Effects of drug addiction are felt by the addict both physically and psychologically. The effects are also seen in those around the addict, like family members. American Society of Addiction Medicine.